Compositions and Methods for the Storage of Red Blood Cells
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United States of America Patent
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Issued Date -
Nov 20, 2014
app pub date -
Apr 18, 2014
filing date -
Feb 18, 2004
priority date (Note) -
Abandoned
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Abstract
The present invention provides an aqueous composition for storage of red blood cells consisting essentially of: adenine; dextrose; at least one nonmetabolizable membrane-protectant sugar; and a specifically defined pH buffering system. Also provided are improved methods for preserving red blood cells and methods for increasing the viability, membrane retention, and recoverability while suppressing apoptosis, hemolysis, and post-reinfusion clearance of stored red blood cells which utilize the novel compositions.
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