Thrombin-binding antibody molecules and uses thereof

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United States of America Patent

PATENT NO 9518129
APP PUB NO 20140370008A1
SERIAL NO

14363514

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This invention relates to isolated antibodies which recognize the exosite 1 epitope of thrombin and selectively inhibit thrombin without promoting bleeding. These antibody molecules may be useful in the treatment and prevention of thrombosis, embolism and other conditions mediated by thrombin.

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Patent Owner(s)

  • JANSSEN PHARMACEUTICALS, INC.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baglin, Trevor Cambridge, GB 16 57
Huntington, James Andrew Cambridge, GB 19 31
Langdown, Jonathan Cambridge, GB 10 28

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