FC VARIANTS WITH REDUCED EFFECTOR FUNCTIONS

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United States of America Patent

APP PUB NO 20140378663A1
SERIAL NO

14128828

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method for producing a variant of a parent polypeptide including a Fc region, which variant exhibits reduced binding to the protein C1q and to at least one receptor Fcgγ R as compared to the parent polypeptide.

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Patent Owner(s)

Patent OwnerAddress
LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIESLES ULIS

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bouayadi, Khalil Ramonville Saint Agne, FR 11 80
Fontayne, Alexandre La Madeleine, FR 14 23
Jorieux, Sylvie Villeneuve D'Ascq, FR 15 155
Kharrat, Abdelhakim Montgiscard, FR 8 73
Mondon, Philippe Donneville, FR 48 318
Monnet-Mars, Celine Blagnac, FR 4 65

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