Method for Inducing a TRIF-Bias

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United States of America Patent

APP PUB NO 20150004180A1
SERIAL NO

14139074

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Abstract

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Compositions comprising a selected aminoalkyl glusoaminide 4-phosphate (AGP) CRX-547 to induce a TRIF-biased response in a human system, which results in reduced levels of MyD88-dependent cytokines relative to the MyD88-dependent cytokines induced by its diastereomer AGP CRX-527.

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Patent Owner(s)

Patent OwnerAddress
GLAXOSMITHKLINE BIOLOGICALS S A1330 RIXENSART

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BOWEN, WILLIAM S Hamilton, US 3 0
EVANS, Jay T Hamilton, US 13 60
HUTTON, MELINDA M Hamilton, US 3 0
JOHNSON, DAVID A Hamilton, US 250 4055
MINNS, LAURIE A Shoreline, US 3 0

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