Fermentation process for producing a virulence factor from bordetella

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United States of America Patent

PATENT NO 9475848
APP PUB NO 20150010948A1
SERIAL NO

14376274

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Abstract

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A process for fermenting Bordetella species comprising incubating a sample of bacteria of a Bordetella species in a first environment under at least one bvg (Bordetella virulence genes) modulating condition, for at least 5 generations, to produce a mature culture, and then incubating the mature culture in a second environment in the absence of the at least one bvg modulating condition.

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Patent Owner(s)

  • GLAXOSMITHKLINE BIOLOGICALS SA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dehottay, Philippe Marc Helene Rixensart, BE 11 21
Goffin, Philippe Rixensart, BE 9 20

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