EARLY BIOMARKERS OF AGE-RELATED LOW-GRADE INFLAMMATION

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United States of America Patent

SERIAL NO

14491635

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Abstract

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The present invention relates to a method for predicting the risk of acquiring an age-related low-grade inflammation for a subject, said method comprising a) providing a biological sample from a subject, b) determining in said sample the level of at least one biomarker selected from the group consisting of a compound of molecular weight between 859-863 g/mol and which is an alkylacylphosphatidylcholine, a compound of molecular weight between 861-865 g/mol and which is a diacylphosphatidylcholine, a compound of molecular weight between 791-794 g/mol and which is an alkylacylphosphatidylcholine, a compound of molecular weight between 522-525 g/mol and which is a monoacylphosphatidylcholine, octadecanoylcarnitine (C18), and tryptophan, c) comparing the level of the at least one biomarker to a reference level, and d) determining whether said subject is likely to be at risk of acquiring an age-related low-grade inflammation, when the level of biomarker(s) deviate significantly from the respective reference level.

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Patent Owner(s)

Patent OwnerAddress
NESTEC S A1800 VEVEY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brahmbhatt, Viral Epalinges, CH 9 67
Breuille, Denis Lausanne, CH 59 376
Guy, Philippe Alexandre Lucens, CH 18 30
Montoliu, Ivan Roura Lausanne, CH 1 1
Papet, Isabelle Clermont-Ferrand, FR 4 23
Vidal, Karine Lausanne, CH 14 52

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