Variant AAV and compositions, methods and uses for gene transfer to cells, organs and tissues

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United States of America Patent

PATENT NO 9840719
SERIAL NO

14338200

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Abstract

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The invention relates to adeno-associated virus (AAV) serotype AAV-Rh74 and related AAV vectors, and AAV-Rh74 and related AAV vector mediated gene transfer methods and uses. In particular, AAV-Rh74 and related AAV vectors target polynucleotides to cells, tissues or organs for expression (transcription) of genes encoding therapeutic proteins and peptides, and polynucleotides that function as or are transcribed into inhibitory nucleic acid sequences.

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Patent Owner(s)

  • THE CHILDREN'S HOSPITAL OF PHILADELPHIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Anguela, Xavier Philadelphia, US 23 173
High, Katherine Merion, US 3 59
Yazicioglu, Mustafa Philadelphia, US 3 51

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