MONITORING IMMUNE RESPONSIVENESS TO CANCER VACCINATION

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United States of America Patent

APP PUB NO 20150038346A1
SERIAL NO

14383102

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention is direct to a method for determining a cancer patient's immune responsiveness to anti-cancer vaccination. In one aspect, for each of a plurality of vaccinations, pairs of clonotype profiles are obtained, one immediately prior to vaccination and one during the period of peak immune response, usually within two to twenty days after the vaccination. Responsiveness is correlated to successive increases in identical clonotypes within each pair of clonotype profiles in at least two successive vaccinations.

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Patent Owner(s)

Patent OwnerAddress
ADAPTIVE BIOTECHNOLOGIES CORP1551 EASTLAKE AVE E SUITE 200 SEATTLE WA 98102

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Faham, Malek South San Francisco, US 97 5030
Klinger, Mark South San Francisco, US 23 550

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