METHODS FOR DETECTING TRISOMY 21
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United States of America Patent
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Issued Date -
Feb 5, 2015
app pub date -
Nov 30, 2012
filing date -
Dec 1, 2011
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Abstract
Methods for determining whether a subject, such as a fetus, has Down syndrome are described. In one embodiment, the methods include detecting one or more biomarkers in a biological sample, and determining whether the expression of the biomarkers is altered when compared to expression of the biomarkers in one or more subjects that do not have trisomy 21. In one embodiment, the biological sample is a blood sample, and the biomarkers are cell free plasma RNAs.
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