SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS

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United States of America Patent

SERIAL NO

14199265

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Abstract

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The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.

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Patent Owner(s)

Patent OwnerAddress
MILLENNIUM PHARMACEUTICALS INCCAMBRIDGE MA 02139

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ammoscato, Vince Riverview, US 14 29
Bishop, John E Groton, US 34 639
Chiu, Fang-Ting Petersburg, US 23 259
Geiser, Achim Hunzenschwil, CH 15 48
Gomez, Jean-Marc Bubendorf, CH 14 48
Hett, Robert Hunzenschwil, CH 25 238
Koellner, Christoph Bubendorf, CH 18 59
Kulkarni, Vithalanand R Petersburg, US 13 30
Lo, Young Petersburg, US 14 29
Munk, Stephen Riverview, US 14 29
Pickersgill, I Fraser Newton, US 13 48

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