Detection, prevention, and treatment of anthrax and other infectious diseases

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United States of America Patent

PATENT NO 9435804
APP PUB NO 20150050292A1
SERIAL NO

13967259

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Compositions and methods for the detection, prevention, or treatment of anthrax or other infectious diseases. In one aspect, the present invention provides methods for immunizing humans or animals against Bacillus anthracis or other capsulated pathogens. The methods include administering a capsular polypeptide of a pathogen of interest and a CD40 agonist to a human or animal. The capsular polypeptide or the CD40 agonist is administered in such an amount or frequency that an immunoprotective response can be elicited in the human or animal against the pathogen of interest. In another aspect, the present invention provides methods of using passive immunization with anti-capsular polypeptide antibodies to prevent or treat infections caused by Bacillus anthracis or other pathogens. In yet another aspect, the present invention provides methods useful for diagnosis of anthrax by detection of capsular polypeptide in serum or other biological samples.

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Patent Owner(s)

  • REGENTS OF THE UNIVERSITY OF MINNESOTA;BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO;STC.UNM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blazar, Bruce R Golden Valley, US 37 148
Brandt, Suzanne Boise, US 3 7
Kozel, Thomas Reno, US 3 1
Lovchik, Julie A Albuquerque, US 3 7
Lyons, C Rick Ft. Collins, US 3 6
Murphy, William Reno, US 48 774
Percival, Ann Reno, US 3 7
Thorkildson, Peter Reno, US 3 7

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