DRUG CONTAINING CARRIER INTO CELL FOR FORMING IMMUNE COMPLEX
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United States of America Patent
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Feb 26, 2015
app pub date -
Nov 30, 2012
filing date -
Nov 30, 2011
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Abstract
The present inventors discovered that by forming a large immune complex comprising antigens containing two or more antigenic binding units (epitopes) and two or more antigen-binding molecules (for example, antibodies), elimination from the plasma of the antigens containing two or more antigenic binding units can be accelerated. Moreover, they found that by using this characteristic and by further using antigen-binding molecules having an ion-dependent antigen-binding activity, elimination of the antigens can further be accelerated and the above problem can be solved.
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