AMPEROMETRIC DETECTION OF LIMULUS AMEBOCYTE LYSATE ACTIVATION BY ENDOTOXIN AND/OR 1-3-BETA-D-GLUCAN
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United States of America Patent
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Mar 5, 2015
app pub date -
Nov 14, 2014
filing date -
Mar 15, 2013
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Abstract
Devices to detect detecting endotoxin (lipopolysaccharide or LPS) and/or 1-3-β-D-glucan (beta glucan or BG) using substrates including electrogenic mediators for amperometric detection are provided herein. Substrates include an amine group as well as one or more substituted organic rings, such as a phenol. Devices include cartridges for detecting LPS or BG simultaneously using dual detection techniques.
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