PROTEASES COMPRISING ONE OR MORE COMBINABLE MUTATIONS
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United States of America Patent
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Issued Date -
Mar 5, 2015
app pub date -
Nov 10, 2014
filing date -
Nov 11, 2008
priority date (Note) -
Abandoned
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Abstract
The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided.
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