CHARACTERIZATION AND ANALYSIS OF THE COMPOSITION AND DYNAMICS OF THE MAMMALIAN RIBOPROTEOME

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United States of America Patent

APP PUB NO 20150079590A1
SERIAL NO

14489018

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Abstract

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The present invention relates to methods for identifying compounds that modulate the translation machinery and methods of diagnosing cancer related to deregulation of the translation machinery. In particular, the methods and diagnostic tests include determining an association between one or more targets and one or more components of the riboproteome and treating a subject with cancer by administering a compound that modulates the association between one or more targets and one or more components of the riboproteome.

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Patent Owner(s)

Patent OwnerAddress
BETH ISRAEL DEACONESS MEDICAL CENTER INC330 BROOKLINE AVENUE BOSTON MA 02215

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CLOHESSY, John Boston, US 1 4
PANDOLFI, Pier Paolo Boston, US 37 109
RESCHKE, Markus Boston, US 7 28

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