Medicament, method, and drug delivery device for treatment of ovarian cancer

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United States of America Patent

PATENT NO 10058688
APP PUB NO 20150080847A1
SERIAL NO

14400216

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Abstract

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Drug delivery devices, medicaments, and methods are provided for the intraperitoneal treatment of ovarian cancer. An implantable device for drug delivery includes an elongated, flexible device having a housing defining a reservoir that contains a drug in solid or semi-solid form, and configured to be wholly deployed within the peritoneal cavity of a patient and continuously release a therapeutically effective amount of the drug over a period of at least 24 hours. A medicament includes cisplatin for administration into the peritoneal cavity of a patient continuously over a treatment period of at least 24 hours. A method of drug delivery includes implanting within the peritoneal cavity of a patient an elongated, flexible device having a reservoir containing a drug, solubilizing the drug at least in part with peritoneal fluid, and releasing an effective amount of the solubilized drug from the reservoir continuously for a period of at least 24 hours.

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Patent Owner(s)

  • MASSACHUSETTS INSTITUTE OF TECHNOLOGY; THE GENERAL HOSPITAL CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Birrer, Michael Boston, US 3 13
Cima, Michael J Winchester, US 150 9578
Del, Carmen Marcela Boston, US 2 13
Ye, Hongye Cambridge, US 6 21

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