METHOD FOR GENERATION OF CONDITIONALLY IMMORTALIZED HEMATOPOIETIC PROGENITOR CELL LINES WITH MULTIPLE LINEAGE POTENTIAL
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United States of America Patent
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Mar 26, 2015
app pub date -
Apr 18, 2013
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Apr 20, 2012
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Abstract
The present invention is a method and kits for generating a homogenous population of hematopoietic progenitor cells capable of differentiating into a hematopoietic cell lineage. Whereas the combination of Homeobox-B8 protein and FMS-like tyrosine kinase 3 ligand generate cells with the potential to differentiate into different myeloid and lymphoid cell types, Homeobox-A7 protein and erythropoietin generate cells with the potential to differentiate into erythropoietic or thrombopoietic cell types.
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