Importance

Loading Importance Indicators...

Abstract

A chemical tool and its use in genome surgery includes P2E2 constructs of in, order, a cell penetration component, a DNA binding component and a restriction endonuclease. The method for performing genome surgery includes:

a) providing one or more recombinant of the P2E2 constructs;b) penetrating a cell with the recombinant P2E2 protein construct;c) forming a protein product in the cell by the processes of transcription and translation or by direct introduction of the P2E2 protein construct to the cell;d) attaching the protein product of the P2E2 construct to one or more targeted genomic sequences within the cell; ande) the endonuclease of the P2E2 construct cutting both strands of the genome at target locations.

Loading the Abstract Image...

First Claim