S100 PROTEIN INHIBITORS FOR TREATING LEUKEMIA
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United States of America Patent
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Issued Date -
Apr 23, 2015
app pub date -
Aug 26, 2014
filing date -
Jul 13, 2004
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Abandoned
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Abstract
The present invention relates to a compound, composition and method for reducing or inhibiting the differentiation or development of progenitor blood cells into malignant cells, leukemia cells or physiologically pathological cells. Particularly, the invention describes the use of inhibitors of S100 proteins, including myeloid related proteins. Inhibition of the activity or synthesis of S100 proteins results into reduction or inhibition of the production or proliferation of aberrant and cancer blood cells.
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