Modulated lysine variant species compositions and methods for producing and using the same

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United States of America Patent

PATENT NO 9181337
SERIAL NO

14077988

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Abstract

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The instant invention relates to modulated lysine variant species compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such modulated lysine variant species compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNFα is detrimental, are also provided.

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Patent Owner(s)

  • ABBVIE INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chumsae, Christopher North Andover, US 17 453
Jing, Ying Wellesley, US 13 132
Kaymakcalan, Zehra Westborough, US 52 4399
Perez, Thiele Mayda Vega Alta, US 1 18
Subramanian, Kartik Northborough, US 47 662
Wong, Chee Furng Singapore, SG 11 180
Zeng, Xiaobei Carolina, US 27 738

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