Antibodies that recognize IAPP

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United States of America Patent

PATENT NO 9951131
SERIAL NO

14329475

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides monoclonal antibody 3H6 and related antibodies. The 3H6 antibody binds to an epitope within residues 28-36 of IAPP. The antibodies of the invention are useful, for example, for treating disorders associated with IAPP accumulation, particularly accumulation of IAPP deposits. Such disorders include type 2 diabetes, metabolic syndrome, impaired insulin tolerance, impaired glucose tolerance, insulinomas, and related conditions.

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Patent Owner(s)

  • PROTHENA BIOSCIENCES LIMITED

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barbour, Robin Walnut Creek, US 70 573
Nijjar, Tarlochan S Orinda, US 66 495

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