METHODS FOR DETERMINING CARRIER STATUS

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United States of America Patent

SERIAL NO

14132364

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Abstract

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The invention generally relates to methods for determining carrier status with respect to a condition or disease. In certain embodiments, the method involves exposing a sample to a plurality of molecular inversion probes capable of capturing DNA from at least one genomic region suspected of having an altered copy number and at least one internal control DNA known or suspected to have a stable copy number, capturing and sequencing DNA that binds to the molecular inversion probes, and determining a copy number state of the at least one genomic region based on the sequence results.

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Patent Owner(s)

Patent OwnerAddress
GOOD START GENETICS INC237 PUTNAM AVENUE CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boyden, Eric D Cambridge, US 6 7
Porreca, Gregory Cambridge, US 35 456
Umbarger, Mark Brookline, US 39 632

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