BIOMARKERS OF RESPONSE TO NAE INHIBITORS

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United States of America Patent

SERIAL NO

14354155

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed herein are markers whose mutational status is associated with sensitivity to treatment with NAE inhibitors. Mutational status is determined by measurement of characteristics of markers associated with the marker genes. Compositions and methods are provided to assess markers of marker genes to predict response to NAE inhibition treatment.

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Patent Owner(s)

Patent OwnerAddress
MILLENNIUM PHARMACEUTICALS INC40 LANDSDOWNE STREET CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Benes, Cyril H Brookline, US 2 6
Blakemore, Stephen J Littleton, US 12 22
Blank, Jonathan L Westborough, US 2 6
Llightcap, Eric S Natick, US 1 3
Mulligan, George J Lexington, US 12 92
Schu, Matthew C Somerville, US 3 11
Settleman, Jeffrey E Mill Valley, US 14 777
Smith, Peter G Arlington, US 32 685

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