Novel ChREBP Isoforms and Methods Using the Same
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United States of America Patent
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Issued Date -
May 7, 2015
app pub date -
Jan 22, 2013
filing date -
Jan 24, 2012
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Abstract
The invention provides diagnostic and prognostic methods and methods of evaluating treatment protocols for disorders such as obesity, diabetes, metabolic syndrome, cancer and vascular disease by detecting the levels of a novel isoform of ChREBP, termed ChREBP β. The invention also provides nucleic acids, proteins, reporter constructs based on ChREBP β and methods of identifying one or more agents that modulate the expression of a ChREBP β target gene.
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