Compositions and Imaging Methods Comprising Detectably Labeled Phosphatidylethanolamine-Binding Peptides
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United States of America Patent
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Issued Date -
May 14, 2015
app pub date -
Jan 8, 2015
filing date -
Jul 15, 2002
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Abstract
Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for utilizing these findings in the treatment of cancer and viral infections. Also disclosed are advantageous antibody, immunoconjugate and duramycin-based compositions and combinations that bind and inhibit anionic phospholipids and aminophospholipids, for use in the safe and effective treatment of cancer, viral infections and related diseases.
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