Anti-Siglec-15 antibodies

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United States of America Patent

PATENT NO 9493562
APP PUB NO 20150139982A1
SERIAL NO

14406560

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Antibodies and antigen binding fragments that specifically binds to Siglec-15 are described herein. These antibodies or antigen binding fragments may have the ability of inhibiting differentiation of osteoclasts and/or the ability of inhibiting the bone resorption activity of osteoclasts. Compositions and cells expressing anti-Siglec-15 antibodies or antigen binding fragments are also disclosed herewith. Anti-Siglec-15 antibodies may also be useful for the treatment of bone loss, or bone diseases. Methods for the detection or diagnosis of bone loss or bone-related diseases are also described.

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Patent Owner(s)

  • DAIICHI SANKYO COMPANY, LIMITED

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Filion, Mario Longueuil, CA 38 273
Moraitis, Anna N Laval, CA 9 21
Stuible, Matthew Mont-Royal, CA 5 34
Sulea, Traian Kirkland, CA 41 143
Tremblay, Gilles Bernard La Prairie, CA 38 240

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