IMMUNOMODULATORY METHODS USING NOTCH AGONISTS

United States of America Patent

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Issued Date
May 21, 2015
app pub date
May 7, 2013
filing date
May 10, 2012

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Abandoned

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Abstract

The invention relates to materials and methods for regulating immune pathways using NOTCH and NOTCH agonists. In particular, said agonists may be used in methods for sensitizing CD4+ CD25− cells to CD4+ CD25+ cell-mediated immunosuppression, for enhancing the TGF-β response of CD4+ CD25− cells.

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Patent Owner	Address
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)	101 RUE DE TOLBIAC CEDEX 13 PARIS 75013
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS	3 AVENUE VICTORIA PARIS 75004
UNIVERSITE PARIS EST CRETEIL VAL DE MARNE	61 AVENUE DU GÉNÉRAL DE GAULLE CRETEIL CEDEX 94010

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Inventor Name	Address	# of filed Patents	Total Citations
Hüe, Sophie	Creteil, FR	1	0
Levy, Yves	Creteil, FR	38	424

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IMMUNOMODULATORY METHODS USING NOTCH AGONISTS

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United States of America Patent

14399977

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14399977

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