Cardiovascular Risk Event Prediction and Uses Thereof

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United States of America Patent

APP PUB NO 20150168423A1
SERIAL NO

14145026

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure includes biomarkers, methods, devices, reagents, systems, and kits for the evaluation of risk of a caradiovascular (CV) Event within 5 years. In one aspect, the disclosure provides biomarkers that can be used alone or in various combinations to evaluate risk of a CV event within 5 years. In another aspect, methods are provided for evaluating risk of a CV event within 5 years in an individual, where the methods include detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 1. In a further aspect, methods are provided for evaluating the risk of a CV, where the methods include detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 2. In a further aspect, methods are provided for evaluating the risk of a CV event in an individual, generally within 5 years, where the methods include detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 3.

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Patent Owner(s)

Patent OwnerAddress
MADRYN HEALTH PARTNERS LPC/O MADRYN ASSET MANAGEMENT LP 140 E 45TH STREET 15TH FLOOR SUITE B NEW YORK NY 10017

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
FOREMAN, Trudi Boulder, US 3 21
GILL, Rosalynn Dianne Boulder, US 5 32
MEHLER, Robert Boulder, US 5 21
SINGER, Britta Boulder, US 5 21
STEWART, Alex AE Waltham, US 13 132
WILLIAMS, Stephen Alaric Boulder, US 19 128

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