IMPLANTABLE MATERIAL GRAFTED WITH A CELL ANTIPROLIFERATIVE AND/OR ANTIBACTERIAL FILM AND PROCESS OF GRAFTING THEREOF
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United States of America Patent
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Jun 25, 2015
app pub date -
Jun 14, 2013
filing date -
Jun 15, 2012
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Abstract
An implantable material has at least one external surface grafted with a film including carboxylate and sulfonate functions wherein the film is simultaneously synthesized and grafted directly on the external surface by radical reaction of a source of carboxylate functions, the source being either polymerizable or chemisorbable and polymerizable and a source of sulfonate functions, the source being either polymerizable or chemisorbable and polymerizable. A process for simultaneously synthesizing and grafting a film directly onto at least one external surface of an implantable material, and the use of a grafted implantable material for the manufacture of an antiproliferative and/or antibacterial implantable medical device are also described.
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