TREATMENT OF MUSCULAR DYSTROPHIES AND RELATED DISORDERS
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United States of America Patent
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Issued Date -
Jul 2, 2015
app pub date -
Aug 29, 2014
filing date -
Aug 15, 2001
priority date (Note) -
Abandoned
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Abstract
The invention provides, among other aspects, compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; diseases or conditions associated with an abnormal level or activity of collagen VI; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); and disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation.
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