COMPOSITIONS AND METHODS FOR SELECTIVELY PRODUCING SIRNA

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United States of America Patent

APP PUB NO 20150182601A1
SERIAL NO

14444828

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The disclosure provided herein provides compositions and methods for producing siRNA. Also disclosed are compositions and methods for modulating the production of siRNA. Also disclosed herein are compositions and methods of treating a disease in a subject comprising administering a Dicer enzyme comprising a helicase domain or a mutated Dicer enzyme to a subject. Also disclosed herein are methods of screening for a candidate modulator that modulates siRNA production.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF UTAH RESEARCH FOUNDATION615 ARAPEEN DRIVE SUITE #310 SALT LAKE CITY UT 84108

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aruscavage,, JR Phillip Joseph Salt Lake City, US 2 0
Bass, Brenda L Salt Lake City, US 2 0
Maity, Tuhin S Los Alamos, US 2 0
Welker, Noah C Salt Lake City, US 8 4

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