Composition with Biofilm Dispersal Agents
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United States of America Patent
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Issued Date -
Jul 2, 2015
app pub date -
Aug 8, 2013
filing date -
Aug 8, 2012
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
Embodiments of the presently-disclosed subject matter provide composites that comprise a tissue graft and a biofilm dispersal agent. The tissue graft can be bone tissue graft, a soft tissue graft, or the like. In specific embodiments the tissue graft is a polyurethane graft and in other embodiments the tissue graft is bone particles, such as demineralized bone matrix. The biofilm dispersal agent can be one or more D-amino acids. The presently-disclosed subject matter further includes methods for treating tissue of a subject that comprise administering the present composites as well as methods for manufacturing the present composites.
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