TETRAHYDROISOQUINOLINES AND INTERMEDIATES THEREFOR

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United States of America Patent

APP PUB NO 20150191494A1
SERIAL NO

14661063

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Abstract

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Disclosed are processes for preparing tetrahydroisoquinolines, intermediates useful in the preparation of tetrahydroisoquinolines, processes for preparing such intermediates, and a crystalline form of 6-[(4S)-2-methyl-4-(naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine. Also disclosed are pharmaceutical compositions comprising tetrahydroisoquinolines, methods of using tetrahydroisoquinolines in the treatment of depression and other conditions and methods for obtaining the crystalline form.

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Patent Owner(s)

Patent OwnerAddress
ALBANY MOLECULAR RESEARCH INC21 CORPORATE CIRCLE ALBANY NY 12203

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Amin, Rasidul East Greenbush, US 18 26
Chen, Bang-Chi Cranbury, US 44 260
Cui, Wenge Clifton Park, US 14 97
Hu, Min Schenectady, US 110 691
Isherwood, Matthew Delmar, US 8 37
Liu, Shuang Schenectady, US 193 1607
Lobben, Paul Lawrenceville, US 5 20
Wang, Bei Yardley, US 96 731
Yang, Yuh-Lin Allen Bay Point, US 7 42
Zhao, Rulin Pennington, US 31 167

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