Compositions, kits, and methods for the diagnosis prognosis, monitoring, treatment and modulation of post-transplant lymphoproliferative disorders and hypoxia associated angiogenesis disorders using galectin-1

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United States of America Patent

PATENT NO 10456465
APP PUB NO 20150191536A1
SERIAL NO

14598405

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention is based, in part, on the discovery that galectin-1 (Gal1) plays a role in viral-associated PTLD, e.g., EBV-associated PTLD and hypoxia associated angiogenesis disorders. Accordingly, the invention relates to compositions, kits, and method for diagnosing, prognosing, monitoring, treating and modulating viral-associated PTLD, e.g., EBV-associated PTLD and hypoxia associated angiogenesis disorders.

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Patent Owner(s)

  • DANA-FARBER CANCER INSTITUTE, INC.; THE BRIGHAM AND WOMEN'S HOSPITAL, INC.; CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET); FUNDACION SALES

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kutok, Jeffery L Natick, US 27 318
Ouyang, Jing Sharon, US 18 39
Rabinovich, Gabriel Ciudad de Buenos Aires, AR 7 33
Rodig, Scott J Westwood, US 12 99
Russo, Diego Omar Croci Provincia de Buenos Aires, AR 5 23
Salatino, Mariana Buenos Aires, AR 5 23
Shipp, Margaret A Wellesley, US 19 111
Takeyama, Kunihiko Tokyo, JP 10 69

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