AAV-mediated gene therapy for RPGR X-linked retinal degeneration

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9770491
SERIAL NO

14413884

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

Described herein are methods of preventing, arresting progression of or ameliorating vision loss and other conditions associated with retinitis pigmentosa and x-linked retinitis pigmentosa in a subject. The methods include administering to a subject an effective concentration of a composition comprising a recombinant adeno-associated virus (AAV) carrying a nucleic acid sequence encoding a normal retinitis pigmentosa GTPase regulator (RPGR gene), or fragment thereof, under the control of regulatory sequences which express the product of the gene in the photoreceptor cells of the subject, and a pharmaceutically acceptable carrier.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

  • UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.;THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aguirre, Gustavo D Philadelphia, US 20 58
Beltran, William A Philadelphia, US 11 15
Boye, Sanford L Gainesville, US 24 107
Cideciyan, Artur V Philadelphia, US 6 10
Deng, Wen-Tao Gainesville, US 2 8
Hauswirth, William W Gainesville, US 44 658
Jacobson, Samuel G Penn Valley, US 15 84
Lewin, Alfred S Gainesville, US 21 132

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
7.5 Year Payment $3600.00 $1800.00 $900.00 Mar 26, 2025
11.5 Year Payment $7400.00 $3700.00 $1850.00 Mar 26, 2029
Fee Large entity fee small entity fee micro entity fee
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00