Cytoplasmic Tail Modifications to Boost Surface Expression and Immunogenicity of Envelope Glycoproteins
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United States of America Patent
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Jul 23, 2015
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Jul 26, 2013
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Jul 27, 2012
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Abstract
The invention provides compositions and methods for enhanced expression of a viral envelope protein. The invention provides a composition comprising a cytoplasmic tail modification to enhance surface expression of both HIV and non-HIV viral envelope proteins as wells as other membrane associated proteins resulting in increased immunogenicity.
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