Preparation containing 6,7-unsaturated-7-carbamoyl morphinan derivatives

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United States of America Patent

PATENT NO 10952968
APP PUB NO 20150216804A1
SERIAL NO

14401388

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Abstract

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The solid preparation which improved the dissolution profile and the stability of the 6,7-unsaturation-7-carbamoyl morphinan derivative is provided. When 6,7-unsaturation-7-carbamoyl morphinan derivative, croscarmellose sodium and ferric oxide were contained, not titanium oxide in the solid preparations and the coating solid preparations, a dissolution rate after 15 minutes of the dissolution test is more than 85%, and stability, particularly, light stability can be improve.

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Patent Owner(s)

Patent OwnerAddress
SHIONOGI & CO LTDOSAKA 541-0045

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ichio, Shunji Osaka, JP 5 9
Mashimo, Akira Osaka, JP 93 614
Noguchi, Kouichi Hyogo, JP 21 286
Tamura, Yoshinori Osaka, JP 42 205

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