COMPOUNDS AND METHODS FOR SELECTIVELY TARGETING CANCER STEM CELLS
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United States of America Patent
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Issued Date -
Aug 13, 2015
app pub date -
Sep 6, 2013
filing date -
Sep 6, 2012
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Abstract
Described are compounds and methods useful for selectively targeting cancer stem cells. The compounds preferentially induce differentiation and/or reduce the proliferation of cancer stem cells relative to normal stem cells. Compounds useful for selectively targeting cancer stem cells include polyene macrolides such as Nystatin or Amphotericin B, analogs thereof and pharmaceutically acceptable salts thereof.
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