DETECTION OF ANTIBIOTIC-RESISTANT MICROORGANISMS
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United States of America Patent
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Issued Date -
Aug 20, 2015
app pub date -
Dec 9, 2014
filing date -
Dec 21, 2007
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Abstract
Method of detecting methicillin-resistant S. aureus (MRSA) and methicillin-sensitive S. aureus (MSSA) in a nucleic acid coamplification assay. The invention advantageously reduces the incidence of false-positive MRSA determinations in real-time assays by requiring satisfaction of a threshold criterion that excludes certain co-infections from the MRSA determination. The invention further provides for determination of MSSA, even when the MSSA is present in combination with methicillin-resistant coagulase-negative (MR-CoNS) bacteria at high or low levels.
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