USE OF POST-TRANSCRIPTIONAL GENE SILENCING FOR IDENTIFYING NUCLEIC ACID SEQUENCES THAT MODULATE THE FUNCTION OF A CELL

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United States of America Patent

APP PUB NO 20150232930A1
SERIAL NO

14705433

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Abstract

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Described herein are methods for identifying nucleic acid sequences that modulate the function of a cell, the expression of a gene in a cell, or the biological activity of a target polypeptide in a cell. The methods involve the use of double stranded RNA expression libraries, double stranded RNA molecules, and post-transcriptional gene silencing techniques.

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Patent Owner(s)

Patent OwnerAddress
ALNYLAM PHARMACEUTICALS INC675 WEST KENDALL STREET HENRI A TERMEER SQUARE CAMBRIDGE MA 02142 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
GIORDANO, Tony Phoenixville, US 17 269
PACHUK, Catherine Lansdale, US 17 105
SATISHCHANDRAN, Chandrasekhar Lansdale, US 36 157

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