METHOD FOR PROGNOSIS OF GLOBAL SURVIVAL AND SURVIVAL WITHOUT RELAPSE IN HEPATOCELLULAR CARCINOMA

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United States of America Patent

APP PUB NO 20150232944A1
SERIAL NO

14429515

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to the technical field of hepatocellular carcinoma (HCC) management, and more precisely to the prognosis of HCC aggressiveness and associated therapeutic decisions. The invention provides a new prognosis method of HCC aggressiveness, based on determination in vitro and analysis of an expression profile comprising genes TAF9, RAMP3, HN1, KRT19, and RAN. The invention also provides kits for the prognosis of HCC aggressiveness, and methods of treatment of HCC in a subject based on a preliminary prognosis of said subject HCC aggressiveness.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)101 RUE DE TOLBIAC PARIS 75013
UNIVERSITE PARIS DESCARTES75270 PARIS CEDEX 06
INTEGRAGEN91000 EVRY

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
De, Reynies Aurelien Boulogne-Billancourt, FR 4 8
Laurent-Puig, Pierre Meudon, FR 10 7
Nault, Jean-Charles Paris, FR 4 7
Zucman-Rossi, Jessica Paris, FR 6 16

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