Systems and methods for automated optimization of a multi-mode inductively coupled plasma mass spectrometer
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United States of America Patent
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Jan 15, 2019
Grant Date -
Aug 20, 2015
app pub date -
Feb 13, 2015
filing date -
Feb 14, 2014
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Abstract
The present disclosure provides methods and systems for automated tuning of multimode inductively coupled plasma mass spectrometers (ICP-MS). In certain embodiments, a ‘single click’ optimization method is provided for a multi-mode ICP-MS system that automates tuning of the system in one or more modes selected from among the multiple modes, e.g., a vented cell mode, a reaction cell mode (e.g., dynamic reaction cell mode), and a collision cell mode (e.g., kinetic energy discrimination mode). Workflows and computational routines, including a dynamic range optimization technique, are presented that provide faster, more efficient, and more accurate tuning.
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