Compositions and Methods for Inhibiting Expression of a Gene from the JC Virus
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United States of America Patent
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Issued Date -
Aug 27, 2015
app pub date -
Mar 12, 2015
filing date -
Apr 28, 2006
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a gene from the JC Virus (JC virus genome), comprising an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part of a gene from the JC Virus. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by JC virus expression and the expression of a gene from the JC Virus using the pharmaceutical composition; and methods for inhibiting the expression of a gene from the JC Virus in a cell.
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