MANUFACTURING METHOD FOR A BUTANEDIOL
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United States of America Patent
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Issued Date -
Sep 10, 2015
app pub date -
Aug 20, 2013
filing date -
Sep 24, 2012
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Abstract
A method of manufacturing a butanediol includes a step of culturing a microbe that contains a gene that codes acetoacetyl-CoA synthase that catalyzes a reaction that irreversibly produces acetoacetyl-CoA from acetyl-CoA and malonyl-CoA, acetoacetyl-CoA reductase that catalyzes a reaction that produces 3-hydroxybutyryl-CoA from acetoacetyl-CoA, and an enzyme that catalyzes a reaction for producing a butanediol from 3-hydroxybutyryl-CoA.
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