ASSESSMENT OF BLOOD-BRAIN BARRIER DISRUPTION
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United States of America Patent
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Sep 24, 2015
app pub date -
Jun 1, 2015
filing date -
May 16, 2007
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Abstract
A method of analyzing a blood-brain barrier of a subject is disclosed. A detectable dose of an MRI contrast agent is administered to the subject, and a plurality of magnetic resonance images of the subject's brain are acquired over a predetermined time-period. Two or more of the magnetic resonance images are compared thereamongst so as to determine variations in concentration of the contrast agent in the brain, and blood-brain barrier function is assessed based on the variations.
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