URINE EXOSOME mRNAS AND METHODS OF USING SAME TO DETECT DIABETIC NEPHROPATHY
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United States of America Patent
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Oct 1, 2015
app pub date -
Oct 2, 2013
filing date -
Oct 5, 2012
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Abstract
Embodiments of the invention relate generally to methods of identifying subjects likely to develop diabetes-associated damage to the nephron, or subjects in the early stages of diabetic nephropathy. In particular, several embodiments relate to quantification of diabetic nephropathy-associated RNA isolated from vesicles from patient urine samples is performed to compare a subject to a population having normal nephron function and/or to track progression of diabetic nephropathy in said subject over time.
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