REAGENT FOR IMAGING INTRACELLULAR ACETYLATION
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United States of America Patent
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Oct 1, 2015
app pub date -
Oct 10, 2013
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Oct 11, 2012
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Abstract
A reagent for imaging an advancing intracellular acetylation, for example, an acetylation that is advanced by the action of acetyl-CoA in the mitochondria, at high sensitivity and high efficiency, which comprises a combination of a rhodamine derivative that is substantially non-fluorescent before being acetylated, and emits strong fluorescence after being acetylated, and an acylation catalyst and/or an acylation reaction-promoting agent.
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