MODULATION OF CD40 EXPRESSION

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United States of America Patent

APP PUB NO 20150291960A1
SERIAL NO

14542923

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed herein are antisense compounds and methods for decreasing CD40. Examples of disease conditions that can be ameliorated with the administration of antisense compounds targeted to CD40 include hyperproliferative disorders, graft versus host disease (GVHD), graft rejection, asthma, airway hyperresponsiveness, chronic obstructive pulmonary disease (COPD), multiple sclerosis (MS), systemic lupus erythematosus (SLE), and certain forms of arthritis.

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Patent Owner(s)

Patent OwnerAddress
IONIS PHARMACEUTICALS INC2855 GAZELLE COURT CARLSBAD CA 92010

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bennett, C Frank Carlsbad, US 412 7677
Cowsert, Lex M New Braunfels, US 219 3636
Freier, Susan M San Diego, US 526 6555

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