PROGNOSTIC METHODOLOGY
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United States of America Patent
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Issued Date -
Oct 15, 2015
app pub date -
Aug 9, 2012
filing date -
Aug 15, 2011
priority date (Note) -
Abandoned
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Abstract
The invention concerns a prognostic method for determining at least one, or a combination, of the following: time to first treatment, response to treatment or overall survival for a patient presenting with a disease including or characterised by telomere shortening, comprising an assessment of the longest mean telomere length at which telomere end-end fusion events can be detected and then a determination of the mean telomere length in the fusogenic range (i.e. the range below said mean telomere length at which telomere end-end fusion events can be detected) and the subsequent use of the mean telomere length in the fusogenic range as a prognostic indicator.
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