NOVEL MUCOSAL ADJUVANTS AND DELIVERY SYSTEMS
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United States of America Patent
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Issued Date -
Oct 22, 2015
app pub date -
Oct 29, 2013
filing date -
Oct 29, 2012
priority date (Note) -
Abandoned
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Abstract
Adjuvants comprising chitosan cross-linked with an aldehyde or mannosylated chitosan are provided herein. Methods of making the adjuvants and methods of combining or linking the adjuvants with antigens are also provided. The adjuvant-antigen combinations can be used in vaccine formulations and the vaccine formulations can be used in methods to vaccinate animals against the source of the antigen or to enhance the immune response in a subject.
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